Maternal perinatal undernutrition programs a “brown-like” phenotype of gonadal
نویسندگان
چکیده
Maternal perinatal undernutrition programs a “brown-like” phenotype of gonadal 1 white fat in male rat at weaning 2 3 Fabien Delahaye, Marie-Amélie Lukaszewski, Jean-Sébastien Wattez, Ouma Cisse, Isabelle 4 Dutriez-Casteloot, Isabelle Fajardy, Valérie Montel, Anne Dickes-Coopman, Christine 5 Laborie, Jean Lesage, Christophe Breton and Didier Vieau 6 7 Unité Environnement Périnatal et Croissance EA 4489, Université Lille-Nord de France, 8 Equipe Dénutritions Maternelles Périnatales, SN4, Université de Lille 1, 59655 Villeneuve 9 d’Ascq, France 10 11 Running title: perinatal programming of adipose tissue 12 Corresponding author: Professor Didier Vieau 13 Unité Environnement Périnatal et Croissance (EA 4489), Université Lille-Nord de France, 14 Equipe Dénutritions Maternelles Périnatales, SN4, Université de Lille 1, 59655 Villeneuve 15 d’Ascq, France 16 Tél : +33 3 20 43 43 68 ; Fax : +33 3 20 33 63 49 17 E-mail : [email protected] 18
منابع مشابه
Maternal perinatal undernutrition programs a "brown-like" phenotype of gonadal white fat in male rat at weaning.
Several studies indicate that maternal undernutrition sensitizes the offspring to the development of metabolic disorders, such as obesity. Using a model of perinatal maternal 50% food-restricted diet (FR50), we recently reported that rat neonates from undernourished mothers exhibit decreased leptin plasma levels associated with alterations of hypothalamic proopiomelanocortin system. The present...
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